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Unveiling the Mystery: High Blood Sugar with No Sugar in Urine

High blood sugar, also known as hyperglycemia, is commonly associated with conditions like diabetes. It's a well-known fact that elevated levels of glucose in the bloodstream can often manifest in the urine, leading to a condition called glycosuria. When someone has high blood sugar but doesn't pass sugar in their urine, it can be confusing and needs to be looked at more closely.

There are several reasons why someone might have high blood sugar levels without sugar appearing in their urine:

Renal threshold: Each person has a renal threshold, which is the blood glucose level at which the kidneys start to excrete glucose into the urine. Normally, this threshold is around 180 mg/dL. If blood sugar levels remain below this threshold, all glucose is reabsorbed by the kidneys, and no sugar appears in the urine. Some individuals may have a higher renal threshold, meaning that their kidneys don't start excreting glucose until blood sugar levels are very high.

Early stages of diabetes: In the early stages of type 2 diabetes, the kidneys may still be able to reabsorb glucose, preventing it from being excreted in the urine. This means that high blood sugar levels may not necessarily be accompanied by sugar in the urine.

Insulin resistance: Insulin resistance occurs when the body's cells don't respond effectively to insulin, leading to elevated blood sugar levels. In insulin resistance, the kidneys may still reabsorb glucose efficiently, preventing it from being excreted in the urine.

Medications: Certain medications, can raise blood sugar levels without causing glucose to appear in the urine.

Dehydration: Dehydration can lead to concentrated urine, which may not accurately reflect blood sugar levels. In cases of dehydration, sugar may not appear in the urine even if blood sugar levels are elevated.

Kidney dysfunction: Sometimes, if your kidneys aren't working well, they might not be able to filter sugar into the urine, leading to high blood sugar without sugar in the urine.

The importance of testing urine for sugar in managing diabetes has decreased over time. It doesn't give a real-time picture of your blood sugar levels and can be inaccurate. 

 

Dr Prashant Goyal

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