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Why Regular Health Check-up are Necessary?

“Health is wealth.” It is an old axiom, but most commonly neglected, because of the fast- paced life, sedentary lifestyle, unhealthy food habits, lack of exercise, lack of sleep and stress. People are becoming more and more vulnerable to diseases like diabetes, hypertension, dyslipidemia, heart diseases and various cancers. We pay attention to these factors only when we’ve run out of time. However, the concept of regular/ annual health check-ups for healthy individuals is increasing day by day. Precautionary healthcare is becoming a part of our routine as people are more educated and aware of their health. But, still, majority of the public and health care professionals are speculative regarding the degree if its utility and using these services in a cost-effective manner. Many organizations, all around the world, have made regular health check- ups mandatory for their employees to ensure their workforce stays fit and healthy, working more efficiently and adding to the overall gain
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Falsely Elevated Interleukin-6 (IL-6): The facts

The interleukin-6 (1L-6) is a multifunctional pleiotropic cytokine, and is also known as interferon-ß2 (IFN-ß2), 26 kDa protein, B-cell stimulatory factor-2 (BSF-2), hybridoma/ plasmacytoma growth factor, hepatocyte stimulating factor and macrophage-granulocyte inducing factor 2A (MGI-2A). IL-6 is released by a variety of cell types such as, T cells, B cells, monocytes, fibroblasts, vascular endothelial cells, cardiac myxomas, bladder cell carcinomas, myelomas, astrocytoma and glioblastomas. It has a major role in the mediation of inflammatory and immune response initiated by infection or injury. IL-6 can be elevated with inflammation, infection, autoimmune disorders, cardiovascular diseases, and some cancers also. In few of the cases it has been associated with an increased risk of disease development or worsening prognosis. As the levels of IL-6 are associated with medical diagnosis, therapy, and prognosis, monitoring the fluctuation of its levels may reflect the progression or regre

Ways To Maintain A Health in Rainy Season

Rainy (Monsoon) season are known to make the climate pleasant and adds scenic beauty to the environment. It gives a new life to the earth. However, monsoon also brings along numerous diseases (esp. food borne and mosquito-borne diseases) due to harmful viruses, bacteria and fungus. Common cold, Flu, Stomach Infection, Diarrhoea, Malaria, Dengue, Typhoid, Chikungunya, Viral fever and Allergy are some of the diseases which make it to the top of the list. The common victims are children and people with low immunity.   Enjoy the monsoon rains the healthy way by eating good food and following certain following precautionary measures.   Eat a healthy, balanced diet to keep you fit. Avoid junk food, street food and pre-cut fruits, especially from the roadside stalls. Eat steamed salads instead of raw vegetables. Thoroughly scrub fruits and vegetables under running water before consuming. Better to avoid milk, and chose other milk-products like yogurt, curd, etc. Include more Vitamin-C rich

Clinical significance of NLR, PLR & LMR in COVID-19

The clinical presentation of COVID-19, varies from no symptoms to severe symptoms with complications like acute respiratory failure, acute respiratory distress syndrome, metabolic acidosis, coagulopathy, and septic shock. A full blood count is a routine, inexpensive and easy test that provides information about formed blood contents. Patients with severe COVID-19 disease present with increased leucocytosis, neutrophilia, lymphopenia, eosinopenia and thrombocytopenia than those with non-severe disease. Recently, reports on the feasibility of few new haematological parameters like, Neutrophil to Lymphocyte ratio (NLR) , Lymphocyte to Monocyte ratio (LMR) and Platelet to Lymphocyte ratio (PLR) in predicting prognosis in patients with SARS-CoV-2 infection have been published. The current study shows that these parameters may be a rapid, cost-effective, widely available, useful prognostic factor in the early screening of critical illness in patients with confirmed COVID-19. These parame

COVID-19 IgG (SARS-CoV-2 IgG) Antibody Test for Sero-surveillance

The SARS-CoV-2 IgG Antibody (COVID-19 IgG) test is intended for the qualitative detection of IgG antibodies to SARS-CoV-2 in human blood. The SARS-CoV-2 IgG test is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2, indicating prior infection. Antibodies are proteins produced by the immune system in response to an infection and are specific to that particular infection. They are found in the blood. SARS-CoV-2 IgG Test may help identify if you were exposed to the virus that causes COVID-19 and, if so, whether or not your body has developed antibodies. Although having antibodies usually gives immunity from further infection, there is a lack of evidence on whether having antibodies means you are protected against reinfection with COVID-19 in future.  This antibody develops in most patients at around two weeks after infection and remains in the blood after you have recovered although we do not presently know how long it may persist. Resul

Can Cervical Cancer Be Prevented?

Yes, cervical cancer is one of the most preventable types of cancer.  Cervical cancer is cancer of the cervix, that is the narrow opening into the uterus from the vagina. Cervical cancer is the fourth most common cancer in women in worldwide and second most common in India. The current estimates indicate approximately 1,00,000 new cases diagnosed and 60,000 deaths annually in India.   Cervical cancer is mainly caused by  Human Papillomavirus  (HPV) infection, a sexually transmitted infection. There are more than 100 types of HPV and of these about 15 high-risk types cause most of the cases of cervical cancer, two of these types (16 and 18) are responsible for more than 70% of cervical cancer in India.  Because of slow develops, cervical cancer is also one of the most preventable types of cancer.  Cervical cancer can often be prevented by having regular screenings (Pap smear or/ and HPV detection) to find any pre-cancers and treat them, as well as receiving the HPV vac

Allergy Blood Test: The Facts

An Allergy is an immune system response to a substance that is not typically harmful to our body. These substances are called allergens . The immune system overreacts to these allergens and produces a chemical, histamine that causes allergy symptoms, mild to a life-threatening reaction (known as anaphylaxis ). Approx 20% population will suffer from allergy at sometime in their life.  Symptom: The symptoms of an allergic reaction can vary from mild to severe.  • Skin rashes • Itching • Nasal congestion  • Sore throat • Watery or itchy eyes • Abdominal cramping or pain • Difficulty in swallowing • Nausea or vomiting • Diarrhea • Difficulty in breathing • Wheezing or cough • Dizziness • Anxiety • Flushing or swelling of the face or eye • Weakness • Unconsciousness Sometime severe and sudden allergic reaction can develop within seconds after exposure to an allergen. This type of reaction is known as anaphylactic reaction and

Tips to Protect Yourself from Air Pollution

Air pollution is becoming a major health problem that affects millions of people world-wide. Air Pollution is an undesirable change in the physical, chemical or biological characteristics of air. Air pollution mainly affects respiratory system causing breathing difficulties and lung diseases such as bronchitis, asthma, pneumonia and lung cancer. As air pollution levels rise, people with lung conditions are at higher risk of becoming ill and needing treatment. If you have a lung condition, high levels of pollution can also cause an exacerbation of your symptoms, such as an asthma attack or a COPD flare-up. Here are some simple, effective tips for protecting you and your family from the dangers of air pollution- Avoid morning walks, garden exercises and outdoor activities when pollution levels are high. Keep doing your exercise indoors in a well-ventilated room or gym. Limit the amount of time your child spends playing outdoors if the air quality is unhealthy. Use of anti-pollu

Can CA-125 be used to screen asymptomatic women for ovarian cancer?

The Cancer Antigen 125 (CA-125) is a tumor marker or biomarker that is best known as a marker for ovarian cancer, But CA-125 has limited specificity for ovarian cancer because elevated CA-125 levels can be found in individuals without ovarian cancer. Hence this assay, regardless of level, should not be interpreted as absolute evidence for the presence or absence of malignant disease. The assay value should be used in conjunction with findings from clinical evaluation and other diagnostic procedures. This test is not recommended to screen Ovarian cancer in the general population. The CA-125 is used to monitor therapy during treatment for ovarian cancer. CA-125 is also used to detect relapse of cancer after treatment is complete. It may also be elevated in other malignant cancers, including those originating in the endometrium, Fallopian tubes, lungs, breast and gastrointestinal tract. A number of normal and noncancerous conditions can cause an elevated CA 125 level, includin

Dengue Fever in Pregnancy

Dengue fever is a viral disease caused by any of four closely related serotypes of flavivirus (RNA virus). Aedes mosquito particularly aedes aegyptii is a vector transmitting it to human beings. Most parts of India are dengue epidemis because of overcrowding and poor sanitation and civic bodies. As cases of adult dengue fever increases after monsoons it also affects pregnant females. The clinical manifestations, treatment and outcome of dengue in pregnant women are similar to those of nonpregnant patients. Few areas of concern shall be briefly touched in this article. Classical dengue fever is characterized by sudden high fever, severe headache, retro-orbital pain and non specific body aches. Sometimes, ecchymosis or rash develop or bleeding symptoms appear. Dengue infections can sometimes also accompany potentially fatal complications that can cause shock, bleeding or organ damage.  Hence, a pregnant female should always be worked for suspected dengue infection. Misdiagnosi

Lipemia may produce significant interference in the analytical results of different biochemical parameters.

Lipemia is the increased concentration of triglyceride-rich lipoproteins in blood resulting in the cloudy/turbid appearance of serum or plasma. Lipemia in a blood specimen used for clinical evaluation can cause significant interference with obtaining accurate test values. Lipemia creates turbidity of a sample and is a result of the accumulation of lipid particles (mainly due to the presence of chylomicrons). These large particles create light scatter, resulting in elevated absorbance levels that impact colorimetric determinations. Many clinical analytes are found in the aqueous layer of plasma/serum, thus decreasing certain test values in lipemic specimens, while lipid-soluble analytes may be erroneously elevated.  Lipemia causes clinically significant interferences for level of phosphorus, creatinine, total protein, calcium etc.  Mechanism of Interference Light scattering effects may increase absorbances during end point reactions and non-blanked reactions