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Understanding the Interferon-Gamma Release Assay (IGRA)Test in Diagnosis of Tuberculosis (TB)

Tuberculosis (TB) has been a global health concern for centuries, and it remains a significant public health challenge in many parts of the world. Tuberculosis is a bacterial infection caused by Mycobacterium tuberculosis. It primarily affects the lungs, but it can also target other parts of the body, such as the kidneys, bones, and the central nervous system. Accurate and timely diagnosis of TB is crucial for effective management and control of the disease. One important tool in the fight against TB is the Interferon-Gamma Release Assay (IGRA)Test. IGRA tests, such as the QuantiFERON -TB Gold test and the T-SPOT.TB test, work by measuring the release of interferon-gamma, an immune system protein, in response to specific TB antigens. There are two primary forms of TB: 1. Active TB: This is when the bacteria are actively multiplying and causing symptoms. People with active TB may experience coughing, chest pain, fatigue, weight loss, and fever. 2. Latent TB: In this state, indiv...

Essential Precautions for Blood Tests: Ensuring Accurate and Reliable Results

Before undergoing blood investigations or blood tests, there are some general and test specific precautions / preparations you should consider. These precautions can help ensure the accuracy of the test results and your overall well-being. Here are some common general steps to take: Follow your doctor's instructions: Always follow any specific instructions provided by your doctor. They may have tailored recommendations for your particular tests or medical condition. Fasting requirements: One of the most common instructions for blood tests is fasting. Some blood tests require fasting before the test. This means you should not eat or drink anything (except for water) for a specific period before the test. Typically, fasting for 8 to 12 hours is common for tests like glucose, and triglyceride levels. Follow your doctor's advice regarding fasting. Stay hydrated: It's generally a good idea to drink plenty of water before your blood test. This can make it easier for the ...