Accuprobe Awareness

In the world of medicine, diagnostics play a crucial role in identifying and understanding multiple myeloma and other various diseases. One such diagnostic tool, Serum Protein Electrophoresis (SPEP) , has gained prominence due to its effectiveness in evaluating a patient's overall health and detecting various medical conditions. SPEP is a laboratory technique used to separate and quantify different proteins present in the blood serum. These protein fractions can be broadly categorized into five main types: Albumin: This is the most abundant protein in the blood serum and is responsible for maintaining the osmotic pressure and transporting various substances in the blood. Alpha-1 globulins: These proteins include alpha-1 antitrypsin, alpha-1 acid glycoprotein, and others. They are involved in the regulation of enzymes and the immune system. Alpha-2 globulins: Alpha-2 macroglobulin and haptoglobin are examples of alpha-2 globulins. They play essential roles in inflammation and imm...

  Blood tests are essential tools in diagnosing various medical conditions. However, sometimes these tests can produce misleading results, such as in the case of pseudothrombocytopenia. Before we delve into pseudothrombocytopenia, let's first grasp the significance of platelets. Platelets, also known as thrombocytes, are small cell fragments in the blood produced in the bone marrow. Their primary function is to play a crucial role in haemostasis, preventing excessive bleeding when blood vessels are injured. Pseudothrombocytopenia (Falsely low platelet count) is essentially a laboratory artifact where blood tests show low platelet counts, but the real platelet count is actually normal. It occurs when platelets clump together in the blood sample collected for analysis, leading to inaccurate platelet counts by automated cell counters. Although pseudothrombocytopenia is a benign and relatively rare condition, its accurate identification is essential to prevent unnecessary clinical inte...