Accuprobe Awareness

Both serum IgE (Immunoglobin E) level and blood Absolute Eosinophil Count (AEC) are useful tests in evaluating and diagnosing allergies, but they serve different purposes and have their own strengths and limitations. So, they are often measured together in clinical practice. While IgE and eosinophils are both associated with allergic responses, they do not always change in tandem. It is possible for a person to have high levels of IgE but a normal AEC, or vice versa. This is because allergic reactions are complex and involve multiple components of the immune system, and the specific immune response can vary depending on the type and severity of the allergic condition. IgE is an immunoglobulin that plays a key role in allergic reactions. When a person is expose to an allergen, such as pollen or dust mites, IgE levels in the blood may rise as the immune system mounts an allergic response. High levels of IgE in the blood are often seen in people with allergies, asthma, and other allergic ...

  Iron deficiency without anemia refers to a condition where there is a decrease in the body's iron stores, but the individual's hemoglobin levels are still within the normal range, and they do not meet the diagnostic criteria for anemia. Anemia is a condition characterized by a reduced number of red blood cells or a decrease in the amount of hemoglobin in the blood, which can result in fatigue, weakness, and other symptoms. Iron is an essential mineral that plays a crucial role in carrying oxygen in the blood and supporting various physiological processes in the body. Iron deficiency can occur due to inadequate dietary intake of iron, poor iron absorption by the body, increased iron demands (such as during pregnancy or growth spurts), or chronic blood loss (such as from menstruation or gastrointestinal bleeding). Iron deficiency without anemia can occur in the early stages of iron depletion when the body's iron stores are becoming depleted, but the hemoglobin levels have ...

Prolactin (PRL) is a hormone produced by the pituitary gland in the brain that plays a role in lactation and reproduction.  The elevation of serum PRL levels (hyperprolactinemia) has multiple etiologies that can be divided into physiological, pharmacological, and pathological causes.  There are several potential reasons for a falsely high prolactin level in a blood sample. Prolactin levels of women were significantly higher in the morning than those in the evening. Prolactin is secreted in a circadian and pulsatile pattern. Serum prolactin level reaches its maximum in the early morning hours, returns to the normal value one hour after waking up, and is lower in the evening than that in the morning. Prolactin is often measured in the early morning hours along with other tests that require fasting and is affected by the physiological morning peak. So, it can be falsely higher than the normal range and can lead to further unnecessary investigations.  Certain medications can...